Description

2-(Bromomethyl)-1-Chloro-4-(Trifluoromethoxy)Benzene is a versatile and highly functionalized aromatic building block, essential for advanced organic synthesis. Its unique combination of reactive bromomethyl and chloro substituents, along with the stable trifluoromethoxy group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drug candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional side chains into polymers, altering their solubility, thermal stability, and surface properties for specialty materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	2-(Bromomethyl)-1-Chloro-4-(Trifluoromethoxy)Benzene
CAS No.	1261762-32-6
Molecular Formula	C9H5BrClF3O
Molecular Weight	304.49 g/mol
Synonyms	1-Chloro-2-(bromomethyl)-4-(trifluoromethoxy)benzene; 4-Chloro-3-(trifluoromethoxy)benzyl Bromide; 2-Bromomethyl-1-chloro-4-trifluoromethoxybenzene; α-Bromo-4-chloro-3-(trifluoromethoxy)toluene; (2-Chloro-5-(trifluoromethoxy)phenyl)methyl Bromide; Benzene, 2-(bromomethyl)-1-chloro-4-(trifluoromethoxy)-; 1-Chloro-4-(trifluoromethoxy)-2-(bromomethyl)benzene
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-1-Chloro-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.