Description

3-Chloro-4,5-Difluorobenzaldehyde is a high-value fluorinated aromatic aldehyde building block, essential for the synthesis of complex organic molecules. Its unique halogenated structure provides critical reactivity and electronic properties for advanced material and pharmaceutical development. This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro and chloro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a fundamental building block for fluorinated liquid crystal molecules and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties for high-performance coatings and engineering plastics.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Organic Synthesis & Research: A versatile reagent in academic and industrial research laboratories for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Chloro-4,5-Difluorobenzaldehyde
CAS No.	1261737-50-1
Molecular Formula	C7H3ClF2O
Molecular Weight	176.55 g/mol
Synonyms	3-Chloro-4,5-difluorobenzaldehyde; 4,5-Difluoro-3-chlorobenzaldehyde; Benzaldehyde, 3-chloro-4,5-difluoro-; 3-Chloro-4,5-difluoro-benzenecarboxaldehyde; 1261737-50-1
EINECS	Contact for details

Quality Control

Our 3-Chloro-4,5-Difluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards. We support cGMP and ISO 9001 compliant production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.