Description

2-Fluoro-4-(4-(Trifluoromethoxy)Phenyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethoxy substituents, is engineered to impart desirable properties such as metabolic stability and enhanced lipophilicity to target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is utilized to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine and trifluoromethoxy groups contribute to biological activity and environmental persistence.
• Material Science Research: Employed in the synthesis of functionalized ligands for catalysis and in the development of organic electronic materials.
• Chemical Biology Probes: Serves as a versatile scaffold for designing molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions for clinical trial materials.

Basic Information

Product Name	2-Fluoro-4-(4-(Trifluoromethoxy)Phenyl)Pyridine
CAS No.	1261656-26-1
Molecular Formula	C₁₃H₇F₄NO
Molecular Weight	269.19 g/mol
Synonyms	2-Fluoro-4-[4-(trifluoromethoxy)phenyl]pyridine; 4-(4-(Trifluoromethoxy)phenyl)-2-fluoropyridine; 2-Fluoro-4-(4-trifluoromethoxyphenyl)pyridine; Pyridine, 2-fluoro-4-[4-(trifluoromethoxy)phenyl]-; 1261656-26-1
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(4-(Trifluoromethoxy)Phenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory and manufacturing practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.