Description

3-Cyano-5-Fluorobenzene-1-Sulfonyl Chloride is a versatile and high-value aromatic sulfonyl chloride derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a sulfonyl chloride and a nitrile group on a fluorinated benzene ring, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonamide moiety confers biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced functional materials.
• Chemical Research: A valuable reagent in medicinal chemistry and process development for introducing the sulfonamide functional group.
• Dye and Pigment Industry: Intermediate in the synthesis of complex colorants and photographic chemicals.

Basic Information

Product Name	3-Cyano-5-Fluorobenzene-1-Sulfonyl Chloride
CAS No.	1261644-49-8
Molecular Formula	C7H3ClFNO2S
Molecular Weight	219.62 g/mol
Synonyms	5-Fluoro-3-cyanobenzenesulfonyl chloride; 3-Cyano-5-fluorobenzenesulfonyl chloride; 5-Fluoro-1,3-benzenedicarbonitrile, 2-sulfonyl chloride derivative; 2-Fluoro-6-cyanobenzenesulfonyl chloride; 3-Fluoro-5-cyanobenzenesulfonyl chloride; 5-Fluoro-3-sulfonylchloride benzonitrile; 1261644-49-8; Benzenesulfonyl chloride, 3-cyano-5-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Cyano-5-Fluorobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.