Description

1-Bromo-3-(Difluoromethyl)-2-Methylbenzene is a high-purity, specialized aromatic building block featuring bromine and difluoromethyl substituents. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique halogen and fluorine chemistry enables precise molecular modifications. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material science industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting fluorinated small molecules.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Fluorine Chemistry Research: An important reagent for studying the introduction and effects of the difluoromethyl group in organic synthesis.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Item	Detail
Product Name	1-Bromo-3-(Difluoromethyl)-2-Methylbenzene
CAS No.	1261609-97-5
Molecular Formula	C9H7BrF2
Molecular Weight	233.05 g/mol
Synonyms	2-Bromo-6-(difluoromethyl)toluene; 3-Bromo-2-methylbenzylidene difluoride; 1-Bromo-3-(difluoromethyl)-2-methyl-benzene; 2-Methyl-3-(difluoromethyl)bromobenzene; 1261609-97-5; 3-(Difluoromethyl)-2-methyl-1-bromobenzene; 2-Methyl-α,α-difluoro-3-bromotoluene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Difluoromethyl)-2-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available for every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.