Description

2-Fluoro-5-(4-(Trifluoromethoxy)Phenyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethoxy substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance bioactivity and environmental persistence.
• Material Science Research: Employed in the synthesis of specialty chemicals, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2-Fluoro-5-(4-(Trifluoromethoxy)Phenyl)Pyridine
CAS No.	1261592-34-0
Molecular Formula	C13H7F4NO
Molecular Weight	257.19 g/mol
Synonyms	2-Fluoro-5-[4-(trifluoromethoxy)phenyl]pyridine; 5-(4-(Trifluoromethoxy)phenyl)-2-fluoropyridine; 2-Fluoro-5-(4-trifluoromethoxyphenyl)pyridine; 1261592-34-0; 2-Fluoro-5-(4-(trifluoromethoxy)phenyl)pyridine; Pyridine, 2-fluoro-5-[4-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(4-(Trifluoromethoxy)Phenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.