Description

3,5-Difluoropyridine-2-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound is valued for its role as a key sulfonylation reagent, enabling the introduction of the sulfonyl group into complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that incorporate the difluoropyridine moiety for enhanced bioactivity and stability.
• Material Science Research: Serves as a building block for creating functionalized polymers and advanced materials with specific electronic or surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeling reagents for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3,5-Difluoropyridine-2-Sulfonyl Chloride
CAS No.	1261587-79-4
Molecular Formula	C5H2ClF2NO2S
Molecular Weight	213.59 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 3,5-difluoro-; 3,5-Difluoro-2-pyridinesulfonyl chloride; 3,5-Difluoropyridine-2-sulfonyl chloride; 2,6-Difluoropyridine-3-sulfonyl chloride (tautomer); 3,5-Difluoropyridine-2-sulfonic acid chloride; 1261587-79-4
EINECS	Contact for details

Quality Control

Our 3,5-Difluoropyridine-2-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP standards where applicable, ensuring the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.