Description

5-Bromo-2-Methoxypyridine-3-Sulfonyl Chloride is a high-purity, versatile sulfonyl chloride derivative used as a key synthetic intermediate. Its value lies in its reactive sulfonyl chloride group, which enables efficient coupling reactions for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine-sulfonamide scaffold is prevalent.
• Material Science Research: Serves as a precursor for creating functionalized polymers or organic electronic materials with specific sulfonamide linkages.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle for bioconjugation or as a scaffold in designing enzyme inhibitors and molecular probes.
• Custom Synthesis & Contract Manufacturing: An important reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	5-Bromo-2-Methoxypyridine-3-Sulfonyl Chloride
CAS No.	1261584-19-3
Molecular Formula	C6H5BrClNO3S
Molecular Weight	286.53 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 5-bromo-2-methoxy-; 5-Bromo-2-methoxy-3-pyridinesulfonyl chloride; 5-Bromo-2-methoxypyridine-3-sulfonyl chloride; 2-Methoxy-5-bromopyridine-3-sulfonyl chloride; 1261584-19-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxypyridine-3-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.