Description

4-Bromo-2-Cyanobenzene-1-Sulfonyl Chloride is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. Its unique structure, featuring bromo, cyano, and sulfonyl chloride groups, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging its reactive sites for structural diversification.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Dye & Pigment Manufacturing: Intermediate for synthesizing complex, high-performance dyes and functional pigments.
• Custom Synthesis & Contract Research: A valuable starting material for custom synthesis projects and medicinal chemistry research in CROs and CDMOs.

Basic Information

Product Name	4-Bromo-2-Cyanobenzene-1-Sulfonyl Chloride
CAS No.	1261583-46-3
Molecular Formula	C7H3BrClNO2S
Molecular Weight	280.53 g/mol
Synonyms	4-Bromo-2-cyanobenzenesulfonyl chloride; 2-Cyano-4-bromobenzenesulfonyl chloride; 1-Bromo-3-cyano-4-chlorosulfonylbenzene; Benzenesulfonyl chloride, 4-bromo-2-cyano-; 4-Bromo-2-cyanobenzene-1-sulfonyl chloride; 1261583-46-3
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Cyanobenzene-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation (by IR/NMR), and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.