Description

2-Bromo-3-Methylbenzenesulfonylchloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality, serving as a versatile electrophile for introducing the sulfonyl group and a halogenated aromatic moiety for further cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the bromo-methylbenzene scaffold provides specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in labeling and modifying biomolecules to study protein function and interactions.
• Catalyst & Ligand Development: A starting material for synthesizing complex ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	2-Bromo-3-Methylbenzenesulfonylchloride
CAS No.	1261566-57-7
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	2-Bromo-3-methylbenzenesulfonyl chloride; 3-Methyl-2-bromobenzenesulfonyl chloride; 1-Bromo-2-methyl-6-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 2-bromo-3-methyl-; o-Bromo-m-toluenesulfonyl chloride; 2-Bromo-3-toluenesulfonyl chloride; (2-Bromo-3-methylphenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methylbenzenesulfonylchloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.