Description

4-Chloro-3-Fluoro-5-Methylpyridine Hcl is a high-purity, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the pyridine core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or functional materials.
• Contract Manufacturing (CMO/CDMO): Supplied to custom synthesis organizations for scale-up and commercial production under cGMP guidelines.

Basic Information

Product Name	4-Chloro-3-Fluoro-5-Methylpyridine Hcl
CAS No.	1261488-09-8
Molecular Formula	C7H8Cl2FN
Molecular Weight	204.05 g/mol
Synonyms	4-Chloro-3-fluoro-5-methylpyridine hydrochloride; 3-Fluoro-4-chloro-5-methylpyridine hydrochloride; 5-Methyl-4-chloro-3-fluoropyridine HCl; Pyridine, 4-chloro-3-fluoro-5-methyl-, hydrochloride; 1261488-09-8; 4-Chloro-3-fluoro-5-picoline hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Fluoro-5-Methylpyridine Hcl is produced and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.