Description

1-(5-Fluoro-Pyrimidin-2-Yl)-Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core fused with a fluorinated pyrimidine ring. This compound is critical for medicinal chemistry research and development, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas where its specific heterocyclic structure is advantageous.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1-(5-Fluoro-Pyrimidin-2-Yl)-Piperidine-4-Carboxylic Acid
CAS No.	1261229-85-9
Molecular Formula	C10H10FN3O2
Molecular Weight	223.20 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(5-fluoro-2-pyrimidinyl)-; 1-(5-Fluoropyrimidin-2-yl)piperidine-4-carboxylic acid; 1-(5-Fluoro-2-pyrimidinyl)piperidine-4-carboxylic acid; 1261229-85-9; UNII-9K3Q3K7V8F; 9K3Q3K7V8F; AKOS040757623; F2198-1428; 1-(5-fluoropyrimidin-2-yl)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-Pyrimidin-2-Yl)-Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.