Description

m-Coumaric Acid-[13C3] is a stable isotope-labeled analog of the naturally occurring phenolic acid, where three carbon atoms are replaced with the carbon-13 isotope. This compound is essential for use as an internal standard in quantitative mass spectrometry, enabling precise and accurate measurement of its unlabeled counterpart in complex biological matrices. It is primarily required by analytical laboratories, pharmaceutical R&D departments, and academic research institutions engaged in metabolomics, pharmacokinetic studies, and the analysis of plant-derived compounds.

Application

• Quantitative Mass Spectrometry: Serves as a critical internal standard for the accurate LC-MS/MS quantification of m-coumaric acid in biological fluids, plant extracts, and food samples.
• Metabolomics Research: Used in tracer studies to investigate the metabolic pathways and flux analysis of phenolic acids in plants, microbes, and mammalian systems.
• Pharmaceutical Development: Facilitates precise pharmacokinetic and bioavailability studies of drug candidates or nutraceuticals containing coumaric acid derivatives.
• Food & Beverage Analysis: Enables reliable measurement of m-coumaric acid content for quality control, authenticity testing, and nutritional labeling in products like honey, wine, and fruits.
• Method Development & Validation: Provides a stable isotope-labeled reference material for developing and validating robust analytical methods in compliance with guidelines like ICH Q2(R1).
• Environmental & Agricultural Science: Applied in studies monitoring plant stress responses, phenolic compound biosynthesis, and the environmental fate of related compounds.

Basic Information

Product Name	m-Coumaric Acid-[13C3]
CAS No.	1261170-79-9
Molecular Formula	C613C3H8O3
Molecular Weight	~167.1 g/mol (Contact for exact value)
Synonyms	3-Hydroxycinnamic Acid-[13C3]; (E)-3-(3-Hydroxyphenyl)acrylic Acid-[13C3]; m-Hydroxycinnamic Acid-[13C3]; 3-Coumaric Acid-[13C3]; Isotopically Labeled m-Coumaric Acid; [13C3]-m-Coumaric Acid; 13C Labeled m-Coumaric Acid; 3-(3-Hydroxyphenyl)-2-propenoic Acid-[13C3]
EINECS	Contact for details

Quality Control

Our m-Coumaric Acid-[13C3] is manufactured under controlled conditions to ensure high isotopic and chemical purity, critical for its role as an analytical standard. Each batch undergoes rigorous testing, including HPLC for chemical purity and MS for isotopic enrichment and positional verification. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for purity, isotopic abundance, and solvent content is provided. Our quality system supports traceability and consistency for research and regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C (on the labeled positions)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.