Description

6-Fluoro-2-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-value, multi-fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both fluorine and trifluoromethyl substituents on the imidazopyridine core, makes it a critical intermediate for modulating the physicochemical and pharmacokinetic properties of target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies, where the fluorine atoms can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, such as herbicides and fungicides, leveraging the fluorine motifs to improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing novel fluorinated organic electronic materials, including OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probe Development: Employed in the design of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns under cGMP or ISO standards for clinical and commercial supply.

Basic Information

Product Name	6-Fluoro-2-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	1260903-26-1
Molecular Formula	C8H4F4N2
Molecular Weight	204.13 g/mol
Synonyms	6-Fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridine; 2-(Trifluoromethyl)-6-fluoroimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-fluoro-2-(trifluoromethyl)-; 1260903-26-1; 6-Fluoro-2-trifluoromethylimidazo[1,2-a]pyridine; FC-IMP-26; F-TFMP
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Trifluoromethyl-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Specifications can be tailored to meet specific project requirements, including research-grade to cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.