Description

[3-Fluoro-5-(Trifluoromethyl)Pyridin-2-Yl]Methanamine is a high-value, multi-fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the pyridine ring, makes it an essential intermediate for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in kinase inhibitors, CNS agents, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine motifs improve biological activity and environmental profile.
• Material Science: Serves as a precursor for specialty chemicals, including liquid crystals, organic semiconductors, and advanced polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring novel fluorination chemistry and heterocyclic compound libraries.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	[3-Fluoro-5-(Trifluoromethyl)Pyridin-2-Yl]Methanamine
CAS No.	1260892-22-5
Molecular Formula	C7H6F4N2
Molecular Weight	194.13 g/mol
Synonyms	2-(Aminomethyl)-3-fluoro-5-(trifluoromethyl)pyridine; 1-[3-Fluoro-5-(trifluoromethyl)pyridin-2-yl]methanamine; (3-Fluoro-5-(trifluoromethyl)pyridin-2-yl)methanamine; 3-Fluoro-5-(trifluoromethyl)-2-pyridinemethanamine; 2-Pyridinemethanamine, 3-fluoro-5-(trifluoromethyl)-; 1260892-22-5; FC-1133
EINECS	Contact for details

Quality Control

Our [3-Fluoro-5-(Trifluoromethyl)Pyridin-2-Yl]Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.