Description

3-Fluoropyridine-2-Carboxylic Acid Hydrochloride is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored properties, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials that require the introduction of a fluorinated heterocyclic moiety.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluoropyridine scaffold enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorinated probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-Fluoropyridine-2-Carboxylic Acid Hydrochloride
CAS No.	1260890-41-2
Molecular Formula	C6H5ClFNO2
Molecular Weight	177.56 g/mol
Synonyms	2-Carboxy-3-fluoropyridine hydrochloride; 3-Fluoro-2-pyridinecarboxylic acid hydrochloride; 3-Fluoropicolinic acid hydrochloride; 3-Fluoropyridine-2-carboxylic acid HCl; 3-Fluoro-2-pyridylcarboxylic acid hydrochloride; 2-Pyridinecarboxylic acid, 3-fluoro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 3-Fluoropyridine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.