Description

2,6-Difluorophenethyl Bromide is a versatile fluorinated aromatic building block of significant importance in modern synthetic chemistry. Its value lies in its role as a key intermediate for introducing the 2,6-difluorophenethyl moiety into more complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where the fluorine atoms can dramatically alter biological activity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing central nervous system (CNS) drugs, kinase inhibitors, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorination enhances efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the preparation of specialized fluorinated ligands for catalysis and molecular recognition studies.
• Chemical Biology & Proteomics: Utilized to create chemical probes and affinity tags for studying protein function and interactions.

Basic Information

Product Name	2,6-Difluorophenethyl Bromide
CAS No.	1260790-92-8
Molecular Formula	C8H7BrF2
Molecular Weight	221.04 g/mol
Synonyms	1-(2-Bromoethyl)-2,6-difluorobenzene; 2-(2-Bromoethyl)-1,3-difluorobenzene; (2,6-Difluorophenyl)ethyl Bromide; 2-(2,6-Difluorophenyl)ethyl Bromide; 2-Bromo-1-(2,6-difluorophenyl)ethane; α-Bromo-2,6-difluorophenylethane
EINECS	Contact for details

Quality Control

Our 2,6-Difluorophenethyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.