Description

2-Amino-5-Fluoroisonicotinic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines an amino group and a fluorine atom on the pyridine ring, enabling precise modifications in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research and production of advanced organic electronic materials and fluorinated polymers.
• Chemical Biology: Utilized as a probe or building block in the study of biological processes and enzyme interactions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Amino-5-Fluoroisonicotinic Acid
CAS No.	1260671-28-0
Molecular Formula	C6H5FN2O2
Molecular Weight	156.12 g/mol
Synonyms	5-Fluoro-2-aminopyridine-4-carboxylic Acid; 2-Amino-5-fluoropyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 2-amino-5-fluoro-; 5-Fluoro-2-aminoisonicotinic Acid; 2-Amino-5-fluoro-4-pyridinecarboxylic Acid; AFIPA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Fluoroisonicotinic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.