Description

5-Fluoro-2-(Trifluoromethyl)Pyridin-4-Amine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to innovate new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine motifs improve efficacy and environmental profile.
• Material Science Precursor: Employed in the synthesis of specialty chemicals, ligands for catalysis, and functional materials.
• Life Science Research: Serves as a valuable probe or building block in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Fluoro-2-(trifluoromethyl)pyridin-4-amine
CAS No.	1260663-77-1
Molecular Formula	C6H4F4N2
Molecular Weight	180.10 g/mol
Synonyms	4-Amino-5-fluoro-2-(trifluoromethyl)pyridine; 5-Fluoro-2-(trifluoromethyl)-4-pyridinamine; 2-(Trifluoromethyl)-5-fluoropyridin-4-amine; 4-Pyridinamine, 5-fluoro-2-(trifluoromethyl)-; 5-Fluoro-2-trifluoromethylpyridin-4-ylamine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Trifluoromethyl)Pyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.