Description

Methyl 5-(Chlorosulfonyl)-1-Ethyl-1H-Pyrazole-3-Carboxylate is a high-value, multi-functional chemical intermediate featuring a reactive chlorosulfonyl group and an ester moiety. This compound is critical for the synthesis of advanced molecules, enabling the introduction of sulfonamide or sulfonate functionalities. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the sulfonyl group for bioactivity.
• Material Science Research: Serves as a precursor for functional polymers and advanced materials where sulfonyl groups modify physical properties.
• Chemical Biology Probes: Employed in creating activity-based probes and affinity labels for studying protein function and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 5-(Chlorosulfonyl)-1-Ethyl-1H-Pyrazole-3-Carboxylate
CAS No.	1260659-24-2
Molecular Formula	C7H9ClN2O4S
Molecular Weight	252.67 g/mol
Synonyms	1-Ethyl-5-(chlorosulfonyl)-1H-pyrazole-3-carboxylic acid methyl ester; Methyl 1-ethyl-5-(chlorosulfonyl)-1H-pyrazole-3-carboxylate; 5-(Chlorosulfonyl)-1-ethyl-1H-pyrazole-3-carboxylic acid methyl ester; 1H-Pyrazole-3-carboxylic acid, 5-(chlorosulfonyl)-1-ethyl-, methyl ester; CAS 1260659-24-2
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(Chlorosulfonyl)-1-Ethyl-1H-Pyrazole-3-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material produced under a cGMP-compliant quality system where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.