Description

B-1H-Pyrrolo[2,3-B]Pyridin-3-Ylboronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. This compound is essential for constructing complex molecular architectures via the versatile Suzuki-Miyaura cross-coupling reaction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific heterocyclic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials and functional polymers.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein interactions.
• Academic & R&D Laboratories: A standard reagent for methodological development in cross-coupling chemistry and heterocycle functionalization.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis under controlled GMP-like environments.

Basic Information

Product Name	B-1H-Pyrrolo[2,3-B]Pyridin-3-Ylboronic Acid
CAS No.	1260433-36-0
Molecular Formula	C9H9BN2O2
Molecular Weight	188.00 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridin-3-ylboronic Acid; 3-Boron-1H-pyrrolo[2,3-b]pyridine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (Pinacol Ester Precursor); 7-Azaindol-3-ylboronic Acid; 1H-Pyrrolo[2,3-b]pyridine-3-boronic Acid; 3-Borono-1H-pyrrolo[2,3-b]pyridine; Azaindole-3-boronic Acid
EINECS	Contact for details

Quality Control

Our B-1H-Pyrrolo[2,3-B]Pyridin-3-Ylborin Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ICH guidelines for impurities and can provide material suitable for research under GMP frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.