Description

2-(Trifluoromethoxy)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethoxy substituent imparts enhanced metabolic stability and lipophilicity, making it indispensable for developing novel active compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating next-generation products.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals with unique electronic and surface properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of a trifluoromethoxy-pyridine moiety.

Basic Information

Product Name	2-(Trifluoromethoxy)Pyridine
CAS No.	1258191-34-2
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	2-(Trifluoromethoxy)pyridine; Pyridine, 2-(trifluoromethoxy)-; α-(Trifluoromethoxy)pyridine; 2-Trifluoromethoxypyridine; 2-Pyridyl trifluoromethyl ether; 2-(Trifluoromethoxy)pyridine, 98+%; 2-TFMP; O-Trifluoromethyl 2-pyridyl ether
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.