Description

Mmp-12 Inhibitor CAS NO 1258003-93-8 is a potent and selective small molecule inhibitor of Matrix Metalloproteinase-12 (MMP-12), a key enzyme implicated in tissue remodeling and inflammatory processes. This compound is critical for research and development in the pharmaceutical and biotechnology sectors, offering a targeted tool for studying disease pathways. It is primarily utilized by researchers in drug discovery, academic institutions, and contract research organizations (CROs) focused on inflammatory diseases, chronic obstructive pulmonary disease (COPD), and cancer metastasis.

Application

• Drug Discovery & Development: A key research chemical for screening and validating MMP-12 as a therapeutic target in preclinical studies.
• Inflammatory Disease Research: Used to investigate the role of MMP-12 in conditions such as atherosclerosis, chronic obstructive pulmonary disease (COPD), and rheumatoid arthritis.
• Oncology Research: Employed in studies exploring the enzyme's involvement in tumor progression, angiogenesis, and metastasis.
• Biochemical Assay Development: Serves as a reference standard and positive control in high-throughput screening (HTS) and enzymatic activity assays.
• Academic & Institutional Research: Provides a reliable tool for universities and research institutes studying extracellular matrix biology and protease function.
• Mechanism of Action (MoA) Studies: Essential for elucidating the specific inhibitory pathways and pharmacokinetic/pharmacodynamic (PK/PD) relationships of potential drug candidates.

Basic Information

Product Name	Mmp-12 Inhibitor
CAS No.	1258003-93-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MMP-12 Inhibitor; MMP12 Inhibitor; Matrix Metalloproteinase-12 Inhibitor; (S)-N-Hydroxy-1-(2-methoxyethyl)-4-[[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-4-piperidinecarboxamide; CAS 1258003-93-8; MMP-12i; MMP12i
EINECS	Contact for details

Quality Control

Our Mmp-12 Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and batch-specific data is provided with every shipment to guarantee traceability and consistency for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.