Description

(3-Fluoropyridin-4-Yl)Methanamine Dihydrochloride is a high-purity fluorinated pyridine derivative, specifically a dihydrochloride salt of a primary amine. This compound is a critical pharmaceutical intermediate and organic building block valued for its unique chemical reactivity imparted by the fluorine atom and amine functionality. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in medicinal chemistry for creating kinase inhibitors, receptor antagonists, and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluoropyridine moiety can enhance biological activity and stability.
• Chemical Synthesis Building Block: Serves as a versatile reagent for introducing the (3-fluoropyridin-4-yl)methanamine scaffold into larger molecular architectures via amide coupling, reductive amination, or nucleophilic substitution reactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis or in the synthesis of organocatalysts.
• Life Science Research: Used in biochemical and pharmacological studies as a tool compound for probing biological pathways and protein interactions.
• Material Science: Potential monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.

Basic Information

Item	Detail
Product Name	(3-Fluoropyridin-4-Yl)Methanamine Dihydrochloride
CAS No.	1257535-26-4
Molecular Formula	C6H8Cl2FN2
Molecular Weight	199.05 g/mol
Synonyms	4-(Aminomethyl)-3-fluoropyridine dihydrochloride; (3-Fluoro-4-pyridinyl)methanamine dihydrochloride; 3-Fluoro-4-(aminomethyl)pyridine dihydrochloride; 3-Fluoro-4-pyridinemethanamine dihydrochloride; 4-(Aminomethyl)-3-fluoropyridine hydrochloride (1:2); 1-(3-Fluoropyridin-4-yl)methanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (3-Fluoropyridin-4-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.