Description

Dihydrotestosterone-[13C3] is a stable isotope-labeled analog of the potent endogenous androgen, dihydrotestosterone (DHT). This high-purity reference material is essential for precise quantitative analysis in research and development. It is primarily used by scientists and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors for applications requiring high analytical accuracy, such as mass spectrometry-based assays.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative internal standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the accurate measurement of endogenous DHT levels in biological matrices.
• Metabolic Pathway Tracing: Used in pharmacokinetic and metabolic studies to trace and quantify the biotransformation pathways of androgens and related steroid hormones.
• Clinical Research & Diagnostics: Enables the development and validation of highly sensitive and specific diagnostic assays for endocrine disorders, including androgen insensitivity and prostate-related conditions.
• Pharmaceutical Development: Supports drug discovery and development programs targeting androgen receptors, including the bioanalysis of drug candidates and their metabolites.
• Forensic & Anti-Doping Analysis: Provides a definitive reference for the detection and confirmation of exogenous androgen administration in sports drug testing and forensic toxicology.
• Quality Control & Method Validation: Acts as a certified reference material (CRM) for calibrating instruments and validating analytical methods to ensure data integrity and regulatory compliance (e.g., FDA, EMA).

Basic Information

Item	Detail
Product Name	Dihydrotestosterone-[13C3]
CAS No.	1257527-54-0
Molecular Formula	C19H2813C3O2
Molecular Weight	~ 293.5 g/mol
Synonyms	5α-Dihydrotestosterone-16,16,17-13C3; DHT-[13C3]; 17β-Hydroxy-5α-androstan-3-one-[13C3]; Androstanolone-[13C3]; 5α-Androstan-17β-ol-3-one-[13C3]; NSC 137009-[13C3]; Stable Isotope Labeled DHT; [13C3]-DHT
EINECS	Contact for details

Quality Control

Our Dihydrotestosterone-[13C3] is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for critical analytical applications. Each batch is fully characterized using advanced techniques including NMR, HPLC, and high-resolution mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (typically >99 atom % 13C), chemical purity, and analytical results, supporting compliance with GMP/GLP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.