Description

4-(5-Fluoro-2-Pyridinyl)Benzenemethanol is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a benzylic alcohol and a fluoropyridine moiety, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluoropyridine group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for biochemical and diagnostic applications.
• Custom Synthesis and Scale-up: Available for contract research organizations (CROs) and CDMOs for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	4-(5-Fluoro-2-Pyridinyl)Benzenemethanol
CAS No.	1257426-54-2
Molecular Formula	C12H10FNO
Molecular Weight	203.21 g/mol
Synonyms	4-(5-Fluoropyridin-2-yl)benzyl alcohol; (4-(5-Fluoropyridin-2-yl)phenyl)methanol; 2-(4-(Hydroxymethyl)phenyl)-5-fluoropyridine; 5-Fluoro-2-(4-(hydroxymethyl)phenyl)pyridine; Benzenemethanol, 4-(5-fluoro-2-pyridinyl)-; 4-(5-Fluoro-2-pyridyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our 4-(5-Fluoro-2-Pyridinyl)Benzenemethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.