Description

5-Bromo-2-Cyanobenzene-1-Sulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites—the sulfonyl chloride and the nitrile group—which enable precise and efficient construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for creating sulfonamide-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with sulfonamide moieties.
• Material Science: Used in the preparation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of activity-based probes (ABPs).
• Custom Synthesis & Contract Manufacturing: A versatile starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	5-Bromo-2-Cyanobenzene-1-Sulfonyl Chloride
CAS No.	1257415-88-5
Molecular Formula	C7H3BrClNO2S
Molecular Weight	280.53 g/mol
Synonyms	2-Cyano-5-bromobenzenesulfonyl chloride; 5-Bromo-2-cyanobenzenesulfonyl chloride; 3-Bromo-6-(chlorosulfonyl)benzonitrile; 2-Cyanobenzene-1-sulfonyl chloride, 5-bromo derivative; Benzonitrile, 3-bromo-6-(chlorosulfonyl)-; 5-Bromo-2-cyanophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Cyanobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to ISO 9001 standards, and we support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Keep away from strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.