Description

3-Fluoro-1,3'-Biazetidine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which incorporates both a strained azetidine ring and a strategic fluorine atom, enabling precise modulation of molecular properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance bioavailability and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the research and development of specialty polymers and advanced materials with tailored electronic or surface properties.
• Fluorine Chemistry Building Block: A versatile starting material for introducing the 3-fluoroazetidine motif into more complex molecular architectures via cross-coupling or ring-opening reactions.
• Academic & Contract Research: Essential for fundamental research in heterocyclic and fluorine chemistry at universities and contract research organizations (CROs).

Basic Information

Product Name	3-Fluoro-1,3'-Biazetidine
CAS No.	1257293-80-3
Molecular Formula	C6H9FN2
Molecular Weight	128.15 g/mol
Synonyms	1,1'-(3-Fluoroazetidine-1,3-diyl)bis(azetidine); 3-Fluoro-1,3'-biazetidine; 3-Fluoro-1,3'-diazetidine; 3-Fluoro-1,3'-bis(azetidine); 3-Fluoro-1,3'-azetidinylazetidine; 3-Fluoro-1,3'-linked biazetidine; 3-Fluoro-1,3'-diazacyclobutane dimer; Fluorinated biazetidine building block
EINECS	Contact for details

Quality Control

Our 3-Fluoro-1,3'-Biazetidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP conditions for non-clinical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.