Description

3-Amino-5-Fluoro-Pyridin-2-Ol is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which enables the introduction of both amino and fluoro substituents onto a pyridine scaffold, facilitating the development of novel molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), intermediates, and other specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its fluorine-containing heterocyclic structure.
• Ligand and Catalyst Development: Serves as a versatile ligand for metal complexes in catalytic applications.
• Material Science Research: Employed in the creation of organic electronic materials and functional dyes.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic research.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for bespoke chemical synthesis projects.

Basic Information

Product Name	3-Amino-5-Fluoro-Pyridin-2-Ol
CAS No.	1257069-38-7
Molecular Formula	C5H5FN2O
Molecular Weight	128.10 g/mol
Synonyms	2-Hydroxy-3-amino-5-fluoropyridine; 5-Fluoro-2-hydroxy-3-aminopyridine; 3-Amino-5-fluoropyridin-2(1H)-one; 3-Amino-5-fluoro-2-pyridinol; 5-Fluoro-3-amino-2-pyridone; 3-Amino-5-fluoro-2(1H)-pyridinone; 1257069-38-7
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Fluoro-Pyridin-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.