Description

Methyl 3-Fluoro-5-Hydroxypyridine-2-Carboxylate is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a carboxylate ester, a fluorine substituent, and a hydroxyl group, enabling precise structural modifications. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, including kinase inhibitors and other biologically relevant molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research: Serves as a versatile precursor in academic and industrial laboratories for heterocyclic chemistry and fluorination studies.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials and functionalized polymers.

Basic Information

Product Name	Methyl 3-Fluoro-5-Hydroxypyridine-2-Carboxylate
CAS No.	1256836-96-0
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-fluoro-5-hydroxy-, methyl ester; Methyl 3-fluoro-5-hydroxypicolinate; 3-Fluoro-5-hydroxypicolinic acid methyl ester; 3-Fluoro-5-hydroxy-2-pyridinecarboxylic acid methyl ester; Methyl 3-fluoro-5-hydroxy-2-pyridinecarboxylate; 1256836-96-0; 3-Fluoro-5-hydroxypyridine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Fluoro-5-Hydroxypyridine-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.