Description

1-(6-Chloro-5-Fluoro-Pyridin-3-Yl)-Ethanone is a high-purity fluorinated pyridine derivative, a crucial advanced intermediate in modern organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel compounds targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the fluoropyridine moiety.
• Material Science Research: Serves as a precursor for creating functionalized ligands and monomers used in advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(6-Chloro-5-Fluoro-Pyridin-3-Yl)-Ethanone
CAS No.	1256824-98-2
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	1-(6-Chloro-5-fluoropyridin-3-yl)ethanone; 3-Acetyl-6-chloro-5-fluoropyridine; 6-Chloro-5-fluoro-3-acetylpyridine; Ethanone, 1-(6-chloro-5-fluoro-3-pyridinyl)-; 1-(6-Chloro-5-fluoropyridin-3-yl)ethan-1-one; 3-Acetyl-5-fluoro-6-chloropyridine; 5-Fluoro-6-chloro-3-acetylpyridine
EINECS	Contact for details

Quality Control

Our 1-(6-Chloro-5-Fluoro-Pyridin-3-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.