Description

4-Chloro-6-Fluoronicotinaldehyde is a high-purity, versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Employed as a precursor for synthesizing functionalized ligands, organic electronic materials, and liquid crystals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects, supporting R&D and scale-up activities for specialized chemical entities.

Basic Information

Product Name	4-Chloro-6-Fluoronicotinaldehyde
CAS No.	1256824-38-0
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	6-Fluoro-4-chloronicotinaldehyde; 4-Chloro-6-fluoropyridine-3-carboxaldehyde; 3-Pyridinecarboxaldehyde, 4-chloro-6-fluoro-; 4-Chloro-6-fluoro-3-formylpyridine; 4-Chloro-6-fluoronicotin-3-aldehyde; 4-Chloro-6-fluoronicotin-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoronicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be handled under an inert atmosphere to prevent oxidation and stored away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.