Description

1-(5-Bromo-6-Fluoropyridin-3-Yl)Ethanone is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the introduction of both bromine and fluorine substituents in strategic positions for structure-activity relationship (SAR) studies. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the bromo-fluoro substitution pattern can enhance biological activity and environmental profile.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in medicinal chemistry for fragment-based drug discovery and bioconjugation.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	1-(5-Bromo-6-Fluoropyridin-3-Yl)Ethanone
CAS No.	1256822-63-5
Molecular Formula	C7H5BrFNO
Molecular Weight	218.03 g/mol
Synonyms	5'-Bromo-6'-fluoro-3'-acetylpyridine; 3-Acetyl-5-bromo-6-fluoropyridine; 1-(5-Bromo-6-fluoropyridin-3-yl)ethan-1-one; Ethanone, 1-(5-bromo-6-fluoro-3-pyridinyl)-; 5-Bromo-6-fluoro-3-acetylpyridine
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-6-Fluoropyridin-3-Yl)Ethanone adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC-MS, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.