Description

3-Fluoro-5-Methylpicolinaldehyde is a high-purity fluorinated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a fluorine substituent, makes it an essential precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials, liquid crystals, and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	3-Fluoro-5-Methylpicolinaldehyde
CAS No.	1256822-25-9
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	5-Methyl-3-fluoropicolinaldehyde; 3-Fluoro-5-methylpyridine-2-carboxaldehyde; 2-Pyridinecarboxaldehyde, 3-fluoro-5-methyl-; 3-Fluoro-5-methyl-2-pyridinecarboxaldehyde; 3-Fluoro-5-picolinaldehyde
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methylpicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should be kept sealed under positive pressure of inert gas after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.