Description

2-Fluoro-3-Methoxypyridine-5-Carboxylic Acid is a high-purity fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and methoxy substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its electron-withdrawing and steric properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic pathway studies and imaging.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2-Fluoro-3-Methoxypyridine-5-Carboxylic Acid
CAS No.	1256819-38-1
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	5-Carboxy-2-fluoro-3-methoxypyridine; 3-Methoxy-2-fluoropyridine-5-carboxylic Acid; 2-Fluoro-3-methoxypyridine-5-carboxylic acid; 2-Fluoro-3-methoxy-5-pyridinecarboxylic acid; 5-Pyridinecarboxylic acid, 2-fluoro-3-methoxy-; 1256819-38-1
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methoxypyridine-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.