Description

Methyl 6-Chloro-4-Fluoropyridine-3-Carboxylate is a high-purity fluorinated pyridine derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its versatile reactivity, serving as a key precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluoropyridine moiety.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Precursor: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Applications: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	Methyl 6-Chloro-4-Fluoropyridine-3-Carboxylate
CAS No.	1256811-66-1
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	Methyl 6-chloro-4-fluoropyridine-3-carboxylate; 6-Chloro-4-fluoropyridine-3-carboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 6-chloro-4-fluoro-, methyl ester; Methyl 6-chloro-4-fluoro-3-pyridinecarboxylate; 6-Chloro-4-fluoro-3-pyridinecarboxylic acid methyl ester; Methyl (6-chloro-4-fluoropyridin-3-yl)carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Chloro-4-Fluoropyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.