Description

3-Fluoro-4-Methoxypyridine-2-Carboxylic Acid is a high-value fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, combining fluorine and methoxy substituents on the pyridine core, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials for electronic applications.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for mechanistic and metabolic studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	3-Fluoro-4-Methoxypyridine-2-Carboxylic Acid
CAS No.	1256810-60-2
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	2-Carboxy-3-fluoro-4-methoxypyridine; 3-Fluoro-4-methoxy-2-pyridinecarboxylic acid; 3-Fluoro-4-methoxypicolinic acid; 4-Methoxy-3-fluoropyridine-2-carboxylic acid; 1256810-60-2; 3-Fluoro-4-methoxypyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-fluoro-4-methoxy-
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-Methoxypyridine-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.