Description

Ethyl 3-Fluoro-5-Methylisonicotinate is a high-purity fluorinated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require fluorinated pyridine motifs for enhanced activity and stability.
• Material Science Research: Acts as a precursor for creating specialized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	Ethyl 3-Fluoro-5-Methylisonicotinate
CAS No.	1256809-70-7
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	Ethyl 3-Fluoro-5-methylpyridine-4-carboxylate; 3-Fluoro-5-methylisonicotinic acid ethyl ester; 4-Pyridinecarboxylic acid, 3-fluoro-5-methyl-, ethyl ester; 5-Methyl-3-fluoropyridine-4-carboxylic acid ethyl ester; Ethyl 5-methyl-3-fluoropyridine-4-carboxylate; 3-Fluoro-5-methyl-4-pyridinecarboxylic acid ethyl ester; Ethyl 3-fluoro-5-methyl-4-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoro-5-Methylisonicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements for advanced intermediate use. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.