Description

4-Methyl-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid group and a trifluoromethyl substituent, makes it an essential intermediate for creating compounds with tailored properties. This chemical is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as by material scientists for specialty polymer and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Precursor: Serves as a starting material for synthesizing complex chelating ligands and organometallic catalysts used in asymmetric synthesis and polymerization processes.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials that require fluorine-containing aromatic units.
• Chemical Biology Probe: Utilized as a core scaffold for designing molecular probes and inhibitors in biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: A vital starting point for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Methyl-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	1256808-78-2
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	6-(Trifluoromethyl)-4-picolinic acid; 4-Methyl-6-(trifluoromethyl)picolinic acid; 2-Pyridinecarboxylic acid, 4-methyl-6-(trifluoromethyl)-; 4-Methyl-6-trifluoromethylpyridine-2-carboxylic acid; 4-Methyl-6-(trifluoromethyl)-2-pyridinecarboxylic acid; 6-Trifluoromethyl-4-methylpicolinic acid; 4-Methyl-6-(trifluoromethyl)-2-carboxypyridine
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are manufactured under a quality system compliant with cGMP principles where applicable. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.