Description

5-Fluoro-3-Methylpicolinic Acid is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular structure, featuring both a picolinic acid core and strategic fluorine and methyl substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the design and synthesis of novel chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors, where its fluorine atom can modulate electronic properties.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and bio-conjugation reagents used in diagnostic and biochemical research.

Basic Information

Product Name	5-Fluoro-3-Methylpicolinic Acid
CAS No.	1256808-59-9
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	3-Methyl-5-fluoropyridine-2-carboxylic acid; 5-Fluoro-3-methyl-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 5-fluoro-3-methyl-; 5-Fluoro-3-methylpicolinate; 5-F-3-Me-Pico-OH
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Methylpicolinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.