Description

3-Fluoro-5-Hydroxypyridine-2-Carboxylic Acid is a high-value fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a hydroxyl group on a fluorinated pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in catalytic systems or as a building block for functionalized materials.
• Chemical Research: Employed in academic and industrial R&D for exploring new reactions and synthesizing fluorinated heterocyclic compounds.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials requiring fluorinated aromatic components.

Basic Information

Product Name	3-Fluoro-5-Hydroxypyridine-2-Carboxylic Acid
CAS No.	1256806-53-7
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	2-Carboxy-3-fluoro-5-hydroxypyridine; 5-Hydroxy-3-fluoropicolinic Acid; 3-Fluoro-5-hydroxypicolinic Acid; 3-Fluoro-5-hydroxypyridine-2-carboxylate; 3-F-5-OH-Pyridine-2-COOH; 1256806-53-7; 3-Fluoro-5-hydroxy-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated pyridine intermediates. Every batch of 3-Fluoro-5-Hydroxypyridine-2-Carboxylic Acid is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support custom purity requirements for critical R&D and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.