Description

Methyl 3-Amino-6-(Trifluoromethyl)Pyridine-2-Carboxylate is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and an ester group adjacent to the electron-deficient pyridine core, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-infectives, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioavailability and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing molecular probes, tags, and linkers due to its derivatizable functional groups.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 3-Amino-6-(Trifluoromethyl)Pyridine-2-Carboxylate
CAS No.	1256794-12-3
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	Methyl 3-amino-6-(trifluoromethyl)picolinate; 3-Amino-6-(trifluoromethyl)picolinic acid methyl ester; 2-Pyridinecarboxylic acid, 3-amino-6-(trifluoromethyl)-, methyl ester; 6-(Trifluoromethyl)-3-aminopicolinic acid methyl ester; Methyl 3-amino-6-trifluoromethylpyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-6-(Trifluoromethyl)Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.