Description

Methyl 6-Amino-5-Fluoropyridine-3-Carboxylate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and ester functional groups on a fluorinated heterocyclic core, makes it indispensable for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced polymers and electronic materials that require fluorinated aromatic components for specific performance characteristics.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.

Basic Information

Product Name	Methyl 6-Amino-5-Fluoropyridine-3-Carboxylate
CAS No.	1256792-42-3
Molecular Formula	C7H7FN2O2
Molecular Weight	170.14 g/mol
Synonyms	6-Amino-5-fluoro-3-pyridinecarboxylic acid methyl ester; Methyl 6-amino-5-fluoronicotinate; 5-Fluoro-6-aminonicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-amino-5-fluoro-, methyl ester; Methyl 5-fluoro-6-aminopyridine-3-carboxylate; 6-Amino-5-fluoropyridine-3-carboxylic acid methyl ester; Methyl 6-amino-5-fluoropyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Amino-5-Fluoropyridine-3-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider keeping the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.