Description

1-(3-Fluoro-5-Methylpyridin-2-Yl)Ethanone is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, catalysts, and functionalized polymers used in advanced material applications.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and tool compounds to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(3-Fluoro-5-Methylpyridin-2-Yl)Ethanone
CAS No.	1256792-41-2
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	2-Acetyl-3-fluoro-5-methylpyridine; 3-Fluoro-5-methyl-2-acetylpyridine; 1-(3-Fluoro-5-methyl-2-pyridinyl)ethanone; Ethanone, 1-(3-fluoro-5-methyl-2-pyridinyl)-; 2-Pyridineethanone, 3-fluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-5-Methylpyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.