Description

3-Fluoro-5-Methoxypyridine-4-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic placement of reactive functional groups—the aldehyde and fluorine substituents—on the methoxypyridine scaffold, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-deficient pyridine core.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Fluoro-5-Methoxypyridine-4-Carbaldehyde
CAS No.	1256792-34-3
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	4-Pyridinecarboxaldehyde, 3-fluoro-5-methoxy-; 5-Methoxy-3-fluoropyridine-4-carbaldehyde; 3-Fluoro-5-methoxy-4-pyridinecarboxaldehyde; 3-Fluoro-5-methoxypyridine-4-carboxaldehyde; 3-Fluoro-5-methoxyisonicotinaldehyde; 3-Fluoro-5-methoxy-4-formylpyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methoxypyridine-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and ensures compliance with global regulatory expectations for advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture absorption. Keep away from strong acids, bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.