Description

2-Fluoro-3-Methoxypyridine-5-Carbaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides requiring specific fluorine-substituted pyridine motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological systems and enzyme activity.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	2-Fluoro-3-Methoxypyridine-5-Carbaldehyde
CAS No.	1256787-60-6
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Formyl-2-fluoro-3-methoxypyridine; 3-Methoxy-2-fluoropyridine-5-carboxaldehyde; 2-Fluoro-3-methoxy-5-pyridinecarboxaldehyde; 2-Fluoro-3-methoxypyridine-5-carboxaldehyde; 5-Pyridinecarboxaldehyde, 2-fluoro-3-methoxy-; (2-Fluoro-3-methoxypyridin-5-yl)methanal
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methoxypyridine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.