Description

8-Iso Misoprostol CAS NO 1256643-55-6 is a synthetic prostaglandin E1 (PGE1) analog and a key intermediate in advanced pharmaceutical research and development. This compound is of significant commercial interest for its role in the synthesis of novel therapeutic agents targeting specific prostaglandin receptors. It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on developing treatments for gastrointestinal, cardiovascular, and gynecological conditions, where precise chemical structure and high purity are critical for efficacy and safety.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel prostaglandin-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in biochemical and pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
• Drug Discovery: Serves as a precursor for developing new therapeutic candidates for ulcer prevention, cytoprotection, and obstetric/gynecological applications.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for prostaglandin analogs under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	8-Iso Misoprostol
CAS No.	1256643-55-6
Molecular Formula	C22H38O5
Molecular Weight	382.54 g/mol
Synonyms	8-Epi Misoprostol; (11α,13E)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; 8-iso PGE1 Methyl Ester; Misoprostol 8-Isomer; 8-epi-Misoprostol; Prostaglandin E1 8-Isomer Methyl Ester
EINECS	Contact for details

Quality Control

Our 8-Iso Misoprostol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with ICH guidelines, and we can support development toward cGMP standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.