Description

2,5-Difluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated pyridine cores in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for constructing complex, fluorinated heterocyclic compounds.
• Suzuki-Miyaura Cross-Coupling: Specifically designed as a boronic ester partner for palladium-catalyzed coupling with aryl/heteroaryl halides.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Item	Details
Product Name	2,5-Difluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1256358-86-7
Molecular Formula	C11H14BF2NO2
Molecular Weight	241.05 g/mol
Synonyms	2,5-Difluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Pyridineboronic acid, 2,5-difluoro-, 1,3,2-dioxaborolane ester; 2,5-Difluoro-3-pyridinylboronic acid pinacol ester; (2,5-Difluoropyridin-3-yl)boronic acid pinacol ester; 2,5-Difluoro-3-(pinacolatoboryl)pyridine; Pinacol (2,5-difluoropyridin-3-yl)boronate; CAS 1256358-86-7
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality protocols are designed to meet the stringent requirements of GMP and ISO environments for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for extended periods to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.