Description

1,3-Bis(Methoxymethyl)-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Boronic Acid is a sophisticated boronic acid derivative that serves as a key building block in modern synthetic chemistry. Its primary value lies in its dual functionality, combining a protected uracil-like core with a boronic acid group, making it an essential intermediate for cross-coupling reactions like the Suzuki-Miyaura reaction. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel nucleoside analogs, antiviral agents, and other bioactive molecules targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: The boronic acid functionality enables efficient carbon-carbon bond formation for constructing complex, drug-like molecules in medicinal chemistry programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating advanced polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries to identify new chemical entities with desired biological activity.

Basic Information

Product Name	1,3-Bis(Methoxymethyl)-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Boronic Acid
CAS No.	1256346-16-3
Molecular Formula	C9H13BN2O6
Molecular Weight	256.02 g/mol
Synonyms	5-Borono-1,3-bis(methoxymethyl)pyrimidine-2,4(1H,3H)-dione; 1,3-Bis(methoxymethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione (Protected form); 5-Boronouracil MOM-protected derivative; 1,3-Di-MOM-5-boronouracil; B-Protected Uracil Boronic Acid; CAS 1256346-16-3
EINECS	Contact for details

Quality Control

Our 1,3-Bis(Methoxymethyl)-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.