Description

5-Amino-2-Bromo-3-Fluoropyridine, 97% is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines amino, bromo, and fluoro substituents on a pyridine ring, enabling precise structural modifications and the introduction of key pharmacophores. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, facilitating the construction of diverse chemical libraries.
• Ligand & Catalyst Development: Utilized in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Amino-2-Bromo-3-Fluoropyridine, 97%
CAS No.	1256276-41-1
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	2-Bromo-3-fluoro-5-aminopyridine; 3-Fluoro-5-amino-2-bromopyridine; 5-Amino-2-bromo-3-fluoropyridine; 2-Bromo-3-fluoropyridin-5-amine; 3-Fluoropyridine-5-amine, 2-bromo derivative; 5-Pyridinamine, 2-bromo-3-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Bromo-3-Fluoropyridine, 97% undergoes rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is analyzed to confirm identity, purity, and impurity profile. Certificates of Analysis (COA) are available upon request, providing detailed chromatographic and spectroscopic data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.